Do you know where it is ?是什么意思

Do you know where it is ?是什么意思 do you know where it is 为什么不是do you know where is it? DO you know ( ) Where's( It is in Hangzhou. 句子哦：it is me who know you do really want to do and where you Do you know（ A.what color is it B.what can he do C.where is Do you know where malaysia is? Do you know where sugar is （? ） Where is his shoes ,do you know? Do you know where Mr.Zhou is? Do you know where my home is? Do you know where is inner mongolia? do you know where her home is