what's the problem和what's wrong、what's the matter 的区别

what's the problem和what's wrong、what's the matter 的区别 what's the matter?和what's wrong?的区别 what's wrong?&what's the matter? what's up 和what's the trouble what's wrong what's the matter what's the matter和what's wrong 的区别如题 What's the matter 和What's the problem有什么区别 what's the matter with和what's wrong with有什么区别 what's the matter with和what's wrong with的区别,用法.后面都可以有with吗? what's wrong?what's up?what's happend?what's the matter?有什么区 What happen...What's the matter ...What's wrong .的用法～后面+什么? what’s the matter? -What's the problem?